If you’re on the hunt for a delicious and healthy meal that packs a punch of flavor, look no further than these Buffalo Chicken Lettuce Wraps! Perfectly spicy, tangy, and oh-so-satisfying, these wraps are not only easy to make in your slow cooker or Instant Pot, but they also bring a refreshing crunch with every bite. Whether you’re enjoying them as an appetizer or a light main dish, these wraps are sure to impress both family and friends. Let’s dive into the details of creating this scrumptious dish!
Why You’ll Love This Recipe

These Buffalo Chicken Lettuce Wraps are a game changer for meal prep and weeknight dinners. They are:
- Quick and Easy: With both slow cooker and Instant Pot options, you can have dinner ready with minimal effort.
- Flavor-Packed: The combination of cayenne pepper sauce and spices creates a mouthwatering experience.
- Healthy: Using lettuce wraps instead of tortillas cuts down on carbs and adds freshness.
- Versatile: Customize with your favorite toppings and veggies!
Shopping List
Here’s what you’ll need to make these fabulous wraps:
- 24 oz boneless skinless chicken breasts
- 1 celery stalk, diced
- 1/2 onion, diced
- 1 clove garlic, minced
- 16 oz fat-free low sodium chicken broth
- 1/2 cup cayenne pepper sauce (I used Frank’s)
- 6 large lettuce leaves (Bibb or Iceberg)
- 1 1/2 cups shredded carrots
- 2 large celery stalks, cut into 2-inch matchsticks
Equipment & Tools
To make these Buffalo Chicken Lettuce Wraps, you’ll need:
- Slow Cooker or Instant Pot: Choose your favorite cooking method for convenience.
- Cutting Board and Knife: For prepping your veggies and chicken.
- Measuring Cups and Spoons: To ensure accurate ingredient measurement.
- Serving Platter: To present your beautiful wraps!
How to Prepare Buffalo Chicken Lettuce Wraps (Slow Cooker, Instant Pot)

Step 1: Prepare the Chicken
Start by placing the 24 oz of boneless skinless chicken breasts into your slow cooker or Instant Pot.
Step 2: Add the Flavor Components
In a bowl, mix together the diced celery, diced onion, minced garlic, and cayenne pepper sauce. Pour this mixture over the chicken, ensuring it’s well-coated.
Step 3: Pour in the Chicken Broth
Add the 16 oz of fat-free low sodium chicken broth to the pot. This will keep the chicken moist and flavorful as it cooks.
Step 4: Cook
– For the Slow Cooker: Cover and cook on low for 6-7 hours or high for 3-4 hours.
– For the Instant Pot: Seal the lid and cook on high pressure for 10 minutes. Allow the pressure to release naturally for 10 minutes before doing a quick release.
Step 5: Shred the Chicken
Once cooked, remove the chicken from the pot and shred it using two forks. Return the shredded chicken to the pot and mix it with the remaining sauce.
Step 6: Prepare the Lettuce Wraps
Wash and dry the lettuce leaves. Place a generous amount of the buffalo chicken mixture into each leaf.
Step 7: Add Toppings
Top your wraps with shredded carrots and matchstick celery for added crunch and nutrition.
Step 8: Serve and Enjoy!
Arrange the wraps on a serving platter and dig in!
Smart Substitutions

If you’re looking to customize this recipe, consider these substitutions:
- Use grilled chicken if you prefer a smoky flavor.
- Swap out the cayenne pepper sauce for BBQ sauce for a different taste profile.
- Add avocado slices for creaminess.
- For a vegetarian option, substitute the chicken with jackfruit.
Notes on Ingredients
When choosing your ingredients, consider the following:
- Make sure the chicken broth is low sodium to control salt levels.
- For the best flavor, use a quality cayenne pepper sauce. Frank’s is a popular choice!
- Feel free to mix in your favorite spices for an extra kick.
Keep-It-Fresh Plan
If you have leftovers, store them in an airtight container in the refrigerator for up to three days. To keep the lettuce fresh, store the chicken mixture separately from the lettuce leaves. This way, you can enjoy your wraps all week long!
Common Questions
Can I use frozen chicken for this recipe?
Yes, you can use frozen chicken! For the Instant Pot, increase the cooking time by about 5 minutes. The slow cooker will work best with thawed chicken for optimal cooking.
What can I serve with these wraps?
These wraps pair wonderfully with a side of Cheesy Buffalo Chicken Pasta Bake With Ranch Drizzle or a fresh salad for a complete meal.
Can I make this recipe ahead of time?
Absolutely! You can prepare the chicken ahead of time and store it in the fridge for up to three days. Just assemble the wraps when you’re ready to eat.
What type of lettuce works best for wraps?
Bibb and Iceberg lettuce are ideal for wraps due to their large, sturdy leaves. They hold up well and provide a nice crunch!
That’s a Wrap
These Buffalo Chicken Lettuce Wraps (Slow Cooker, Instant Pot) are a delightful way to enjoy a classic flavor while keeping it light and healthy. With the ability to customize and the ease of preparation, this recipe is sure to become a staple in your meal rotation. Whether you’re hosting a gathering or enjoying a quiet dinner at home, these wraps bring fun and flavor to the table. So gather your ingredients, follow the steps, and enjoy a tasty meal that everyone will love!

Buffalo Chicken Lettuce Wraps (Slow Cooker, Instant Pot)
Ingredients
Equipment
Method
- Start by placing the 24 oz of boneless skinless chicken breasts into your slow cooker or Instant Pot.
- In a bowl, mix together the diced celery, diced onion, minced garlic, and cayenne pepper sauce. Pour this mixture over the chicken, ensuring it’s well-coated.
- Add the 16 oz of fat-free low sodium chicken broth to the pot. This will keep the chicken moist and flavorful as it cooks.
- For the Slow Cooker: Cover and cook on low for 6-7 hours or high for 3-4 hours.
- For the Instant Pot: Seal the lid and cook on high pressure for 10 minutes. Allow the pressure to release naturally for 10 minutes before doing a quick release.
- Once cooked, remove the chicken from the pot and shred it using two forks. Return the shredded chicken to the pot and mix it with the remaining sauce.
- Wash and dry the lettuce leaves. Place a generous amount of the buffalo chicken mixture into each leaf.
- Top your wraps with shredded carrots and matchstick celery for added crunch and nutrition.
- Arrange the wraps on a serving platter and dig in!
Notes
- Store leftovers in an airtight container in the refrigerator for up to three days.
- To keep lettuce fresh, store the chicken mixture separately from the lettuce leaves.
- Feel free to mix in your favorite spices for an extra kick!
